Simira Diagnostics
ELISA

ANTI PARIETAL CELL ANTIBODY

  • Report in 8 hrs
  • Serum sample

Price

₹2,500

  • Report in 8 hrs
  • Free home sample collection
  • ₹200 off at checkout
  • NABL certified lab

or call 77900 98009

ANTI PARIETAL CELL ANTIBODY

₹2,500

About this test

The anti-parietal cell antibody (APCA) test detects autoantibodies against parietal cells in the stomach lining, which produce acid and intrinsic factor needed for vitamin B12 absorption.

A normal result is negative.

A positive result suggests autoimmune atrophic gastritis and pernicious anemia, found in about 80–90% of cases. This leads to vitamin B12 deficiency, causing anemia, fatigue, numbness, and memory problems, and sometimes iron deficiency.

APCA may also be positive in type 1 diabetes, thyroid disease, and some healthy older adults, so intrinsic factor antibody testing improves accuracy.

Questions about this test

When should I get the ANTI PARIETAL CELL ANTIBODY test?

You should get an anti-parietal cell antibody test if you have low vitamin B12 without a dietary cause, megaloblastic anemia, unexplained iron deficiency, or symptoms like fatigue, numbness, tingling, a sore red tongue, or memory problems. It is also recommended for people with type 1 diabetes, autoimmune thyroid disease, or a family history of pernicious anemia.

How should I prepare for the ANTI PARIETAL CELL ANTIBODY test?

No special preparation or fasting is required for an anti-parietal cell antibody test. Inform your doctor about any vitamin B12 injections or supplements, acid-reducing medicines, or immunosuppressants you take. Bring previous CBC, vitamin B12, iron, and thyroid test reports, along with any endoscopy findings, if available.

Do I require fasting for the ANTI PARIETAL CELL ANTIBODY test?

No, fasting is not required for an anti-parietal cell antibody test. You can eat and drink normally before giving your sample, and the test can be done at any time of day. However, if a vitamin B12 test is ordered alongside it, you may be asked to fast. Follow your lab’s instructions.

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