Simira Diagnostics
ELISA

Anti Musk AbB

  • Report in 8 hrs
  • Serum sample

Price

₹6,200

  • Report in 8 hrs
  • Free home sample collection
  • ₹200 off at checkout
  • NABL certified lab

or call 77900 98009

Anti Musk AbB

₹6,200

About this test

The anti-MuSK antibody test detects autoantibodies against muscle-specific kinase (MuSK), a protein at the nerve-muscle junction that is essential for muscle contraction.

A normal result is negative.

A positive result confirms MuSK myasthenia gravis, found in about 30–50% of patients without AChR antibodies (seronegative MG). It typically causes weakness of the face, throat, neck, and breathing muscles, with difficulty swallowing, slurred speech, and a risk of breathing crises.

Identifying MuSK-MG is important because it responds poorly to pyridostigmine and thymectomy, but well to rituximab and plasma exchange.

Questions about this test

When should I get the Anti Musk AbB test?

You should get an anti-MuSK antibody test if you have symptoms of myasthenia gravis, such as drooping eyelids, double vision, difficulty swallowing or speaking, neck weakness, or breathlessness, but your AChR antibody test is negative. It is also recommended when symptoms mainly affect the face, throat, and breathing muscles, or respond poorly to standard treatment.

How should I prepare for the Anti Musk AbB test?

No special preparation or fasting is required for an anti-MuSK antibody test. Inform your doctor about any steroids, immunosuppressants, rituximab, plasma exchange, or IVIG, as these can lower antibody levels and affect results. Bring your previous AChR antibody report and any nerve conduction or EMG results if available.

Do I require fasting for the Anti Musk AbB test?

No, fasting is not required for an anti-MuSK antibody test. You can eat and drink normally before giving your sample, and the test can be done at any time of day. Inform your doctor about any immunosuppressive treatment, plasma exchange, or IVIG, as these may affect the results.

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