Simira Diagnostics
ELISA

Anti DS DNA IFA

  • Report in 8 hrs
  • Serum sample

Price

₹3,000

  • Report in 8 hrs
  • Free home sample collection
  • ₹200 off at checkout
  • NABL certified lab

or call 77900 98009

Anti DS DNA IFA

₹3,000

About this test

The anti-dsDNA test by IFA detects antibodies against double-stranded DNA using Crithidia luciliae immunofluorescence, a highly specific method.

A normal result is negative.

A positive anti-dsDNA is highly specific for systemic lupus erythematosus (SLE) and helps confirm the diagnosis after a positive ANA. Higher titers often reflect active disease and are linked to lupus nephritis (kidney involvement).

Rising levels may signal a lupus flare, making it useful for monitoring disease activity and treatment response. A negative result does not fully rule out lupus.

Questions about this test

When should I get the Anti DS DNA IFA test?

You should get an anti-dsDNA test by IFA if your ANA test is positive and lupus is suspected, with symptoms like joint pain, facial (butterfly) rash, sun sensitivity, mouth ulcers, hair loss, fever, or swelling and protein in the urine. It is also recommended for monitoring lupus activity, kidney involvement, and treatment response.

How should I prepare for the Anti DS DNA IFA test?

No special preparation or fasting is required for an anti-dsDNA test by IFA. Inform your doctor about any steroids, hydroxychloroquine, or immunosuppressants, as treatment can lower antibody levels. Also mention medicines like TNF inhibitors, which can sometimes cause positive results. Bring your previous ANA report if available.

Do I require fasting for the Anti DS DNA IFA test?

No, fasting is not required for an anti-dsDNA test by IFA. You can eat and drink normally before giving your sample, and the test can be done at any time of day. Inform your doctor about any lupus treatment or immunosuppressants, as these may affect the results.

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