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ASCA IgG
₹4,540
The ASCA IgG test detects IgG antibodies against Saccharomyces cerevisiae (baker’s yeast). It is an important serological marker for inflammatory bowel disease (IBD).
A normal result is negative, below the lab’s cut-off value.
Positive ASCA IgG, particularly with negative p-ANCA, favors Crohn’s disease over ulcerative colitis. When both ASCA IgG and IgA are positive, the result is highly specific for Crohn’s. Positivity is linked to small-intestine involvement, strictures, fistulas, and more aggressive disease.
It may also occur in celiac disease. Results support, but do not replace, colonoscopy and biopsy.
You should get an ASCA IgG test if you have persistent diarrhea, abdominal pain, weight loss, fatigue, blood in stools, or mouth ulcers and anal fistulas, suggesting inflammatory bowel disease. It is especially helpful when doctors need to differentiate Crohn’s disease from ulcerative colitis, and is often tested together with ASCA IgA and p-ANCA.
No special preparation or fasting is required for an ASCA IgG test. Inform your doctor about any steroids, immunosuppressants, or biologic medicines you take for IBD. Bring previous colonoscopy, biopsy, stool calprotectin, and p-ANCA reports if available, as ASCA results are best interpreted alongside these findings.
No, fasting is not required for an ASCA IgG test. You can eat and drink normally before giving your sample, and the test can be done at any time of day. Inform your doctor about any IBD treatment you are taking to help interpret the results correctly.
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