Simira Diagnostics
Biochemistry

Anti Mag Ab

  • Report in 8 hrs
  • Serum sample

Price

₹7,000

  • Report in 8 hrs
  • Free home sample collection
  • ₹200 off at checkout
  • NABL certified lab

or call 77900 98009

Anti Mag Ab

₹7,000

About this test

The anti-MAG antibody test detects IgM antibodies against myelin-associated glycoprotein (MAG), a protein in the protective sheath of peripheral nerves.

A normal result is negative, below the lab’s cut-off value.

A positive result, especially at high levels, indicates anti-MAG neuropathy, a slowly progressive nerve disorder usually affecting older men. It causes numbness and tingling in the feet, imbalance, unsteady walking, and hand tremor. It is often associated with an IgM paraprotein, such as MGUS or Waldenström’s macroglobulinemia.

It guides treatment, as some patients respond to rituximab.

Questions about this test

When should I get the Anti Mag Ab test?

You should get an anti-MAG antibody test if you have slowly progressive numbness or tingling in the feet, unsteady walking or imbalance, or hand tremor, especially when nerve studies show demyelinating neuropathy. It is also recommended when blood tests show an IgM paraprotein (MGUS) or Waldenström’s macroglobulinemia with nerve symptoms.

How should I prepare for the Anti Mag Ab test?

No special preparation or fasting is required for an anti-MAG antibody test. Inform your doctor about any rituximab, steroids, IVIG, or plasma exchange, as these can affect antibody levels. Bring previous nerve conduction study (NCS/EMG) reports and any serum protein electrophoresis or immunofixation results to help interpret the findings.

Do I require fasting for the Anti Mag Ab test?

No, fasting is not required for an anti-MAG antibody test. You can eat and drink normally before giving your sample, and the test can be done at any time of day. Inform your doctor about any immunotherapy, IVIG, or plasma exchange, as these may affect the results.

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