ANTI DNAse B

You should get an anti-DNase B test if you develop joint pain, fever, chest pain, involuntary jerky movements, dark or blood-tinged urine, or facial swelling weeks after a sore throat or skin infection. It is especially useful when the ASO titer is normal but rheumatic fever or post-streptococcal kidney inflammation is still suspected.

No special preparation or fasting is required for an anti-DNase B test. Inform your doctor about any recent sore throat or skin infection, and any antibiotics or steroids you have taken, as these can affect antibody levels. A repeat test after 2–4 weeks may be advised to check for rising levels.

No, fasting is not required for an anti-DNase B test. You can eat and drink normally before giving your sample, and the test can be done at any time of day. Inform your doctor about any recent throat or skin infections and antibiotic use, as these help interpret the results correctly.