Alpha-1 Antitrypsin

You should get an alpha-1 antitrypsin test if you have emphysema or COPD at a young age (before 45), especially as a non-smoker or light smoker, asthma that doesn’t improve with treatment, or unexplained liver disease. It is also recommended for infants with prolonged jaundice, bronchiectasis, and a family history of AAT deficiency.

No special preparation or fasting is usually required for an alpha-1 antitrypsin test. Avoid testing during an acute infection or illness, as inflammation can falsely raise AAT levels. Inform your doctor about pregnancy, oral contraceptives, hormone therapy, or AAT replacement therapy, as these can affect results.

No, fasting is usually not required for an alpha-1 antitrypsin test. You can eat and drink normally before giving your sample, though some labs may recommend a short fast, so follow their instructions. Avoid testing during an acute infection or illness, as inflammation can falsely raise AAT levels.