Simira Diagnostics
Cytogenetics

ALL PANEL C - KARYOTYPING, FISH MLL, PCR t(12;21), PCR t(9;22), PCR t(1;19)

  • Report in 6 hrs
  • Whole Blood sample

Price

₹12,000

  • Report in 6 hrs
  • Free home sample collection
  • ₹200 off at checkout
  • NABL certified lab

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ALL PANEL C - KARYOTYPING, FISH MLL, PCR t(12;21), PCR t(9;22), PCR t(1;19)

₹12,000

About this test

ALL Panel C combines three methods for a complete genetic assessment of acute lymphoblastic leukemia (ALL):

  • Karyotyping: examines all chromosomes, detecting hyperdiploidy (favorable), hypodiploidy (high risk), and complex changes
  • FISH MLL (KMT2A): detects high-risk MLL rearrangements, common in infants
  • PCR t(12;21) ETV6-RUNX1: favorable prognosis
  • PCR t(9;22) BCR-ABL1: high risk; guides tyrosine kinase inhibitors
  • PCR t(1;19) TCF3-PBX1: intermediate risk

This combined approach ensures accurate risk classification, guides treatment intensity and targeted therapy, and provides markers for MRD monitoring.

Questions about this test

When should I get the ALL PANEL C - KARYOTYPING, FISH MLL, PCR t(12;21), PCR t(9;22), PCR t(1;19) test?

An ALL Panel C test is advised by a hematologist at the time of ALL diagnosis, when blood or bone marrow shows lymphoid blast cells. It is ideally done before starting treatment for complete risk assessment, and parts of it may be repeated at relapse or to monitor residual disease.

How should I prepare for the ALL PANEL C - KARYOTYPING, FISH MLL, PCR t(12;21), PCR t(9;22), PCR t(1;19) test?

No fasting is required for an ALL Panel C test on a blood sample. A bone marrow sample is often preferred; inform your doctor about blood thinners or bleeding disorders, and fast only if sedation is planned. Give the sample before starting chemotherapy or steroids. Karyotyping needs fresh, live cells, so samples must reach the lab within 24 hours and must not be frozen.

Do I require fasting for the ALL PANEL C - KARYOTYPING, FISH MLL, PCR t(12;21), PCR t(9;22), PCR t(1;19) test?

No, fasting is not required for an ALL Panel C test when a blood sample is used. You can eat and drink normally. However, if the test is done on a bone marrow sample under sedation, you may need to fast for 4–6 hours. Follow your doctor’s instructions.

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