Simira Diagnostics
Histopathology

ALK ­1 (IHC Marker)

  • Report in 4 days
  • Tissue sample

Price

₹6,000

  • Report in 4 days
  • Free home sample collection
  • ₹200 off at checkout
  • NABL certified lab

or call 77900 98009

ALK ­1 (IHC Marker)

₹6,000

About this test

The ALK-1 IHC test uses immunohistochemistry on a tissue biopsy to detect anaplastic lymphoma kinase (ALK) protein, produced when the ALK gene is rearranged.

ALK positivity helps diagnose ALK-positive anaplastic large cell lymphoma (ALCL), which has a better prognosis than ALK-negative ALCL. It also identifies inflammatory myofibroblastic tumors, rare ALK-positive B-cell lymphomas, and some lung cancers, though lung testing often uses more sensitive clones.

A positive result can guide treatment with ALK inhibitors such as crizotinib, alectinib, or lorlatinib, and helps classify tumors accurately.

Questions about this test

When should I get the ALK ­1 (IHC Marker) test?

An ALK-1 IHC test is advised by a pathologist or oncologist when a biopsy shows lymphoma, especially suspected anaplastic large cell lymphoma, or a tumor of uncertain type such as an inflammatory myofibroblastic tumor. It is also used for some lung cancers, to help decide whether ALK-targeted therapy may be suitable.

How should I prepare for the ALK ­1 (IHC Marker) test?

An ALK-1 IHC test is performed on a tissue biopsy, usually from an existing paraffin block, so no special preparation or fasting is needed. Submit the paraffin blocks or slides along with the histopathology report. If a new biopsy is required, follow your doctor’s instructions, including stopping blood thinners or fasting if sedation is planned.

Do I require fasting for the ALK ­1 (IHC Marker) test?

No, fasting is not required for an ALK-1 IHC test, as it is usually performed on an existing biopsy tissue block. However, if a new biopsy is needed to obtain tissue, you may need to fast if sedation is planned. Follow your doctor’s specific instructions.

More Histopathology tests

See all 96

Not sure this is the right test?

Tell us what your doctor has prescribed and our team will confirm the right test and book it for you.

77900 98009