AFP

You should get an AFP test if you have cirrhosis or chronic hepatitis B or C, usually every 6 months with an ultrasound, to screen for liver cancer. It is also recommended for a liver or testicular mass, during pregnancy screening (15–20 weeks), and for monitoring liver or germ cell cancer treatment and recurrence.

No special preparation or fasting is required for an AFP test. If you are pregnant, tell the lab your exact gestational age, weight, and whether it is a twin pregnancy, as these affect interpretation. Inform your doctor about any liver disease, stop biotin supplements 48–72 hours beforehand, and use the same lab for follow-up tests.

No, fasting is not required for an AFP test. You can eat and drink normally before giving your sample, and the test can be done at any time of day. If you are pregnant, share your exact gestational age with the lab, and stop biotin supplements 48–72 hours beforehand.